翻开APP
首页 课程 直播 书院
|
端粒和端粒酶的感化 - Elizabeth Blackburn P1
存眷
相干课程
课程先容
本视频由科普中国和生物医学大课堂出品

Elizabeth Blackburn (UCSF) Part 1: The Roles of Telomeres and Telomerase

Lecture Overview
Telomerase, a specialized ribonucleprotein reverse transcriptase, is important for long-term eukaryotic cell proliferation and genomic stability, because it replenishes the DNA at telomeres. Thus depending on cell type telomerase partially or completely (depending on cell type) counteracts the progressive shortening of telomeres that otherwise occurs. Telomerase is highly active in many human malignancies, and a potential target for anti-cancer approaches. Furthermore, recent collaborative studies have shown the relationship between accelerated telomere shortening and life stress and that low telomerase levels are associated with six prominent risk factors for cardiovascular disease.
批评
我要征询
讲师先容
  • 讲师:Elizabeth Blackburn(份子生物学家)

    生于澳大利亚、现居美国,具有澳、美两国国籍,现任加利福尼亚大学旧金山分校生归天学与生物物理学系传授。她是端粒和端粒酶钻研范畴的前驱,并因在该范畴的进献而与格雷德和绍斯塔克一路取得2009年诺贝尔心理学或医学奖。